The world of Red Dead Redemption 2 five fictitious U.S. states. The states of New Hanover, Ambarino and Lemoyne are new to the series, and are located to the immediate north and east of Red Dead Redemption's world, whilst the states of New Austin and West Elizabeth return from Red Dead Redemption. The states are centered on the San Luis and Lannahechee Rivers and the shores of Flat Iron Lake. Ambarino is a mountain wilderness, with the largest settlement being a Native American reservation; New Hanover is a wide valley that has become a hub of industry and is home to the cattle town of Valentine; and Lemoyne is composed of bayous and plantations resembling Louisiana, and is home to the Southern town of Rhodes and the former French colony of Saint Denis, analogous to New Orleans. West Elizabeth consists of wide plains, dense forests, and the modern town of Blackwater. This region has been expanded from the original Red Dead Redemption to include a vast northern portion containing the small town of Strawberry. New Austin is an arid desert region centered on the frontier towns of Armadillo and Tumbleweed, also featured in the original game. Parts of New Austin and West Elizabeth have been redesigned to reflect the earlier time; for example, Blackwater is still under development, while Armadillo has become a ghost town because of a cholera outbreak.